Useful references related to Basic Science in Trauma

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2012; Sheth, U., Simunovic, N., Klein, G., Fu, F., Einhorn, T.A., Schemitsch, E., Ayeni, O.R. and Bhandari, M. Efficacy of autologous platelet-rich plasma use for orthopaedic indications: a meta-analysis. J Bone Joint Surg Am: 94; 4. 298 - 307. Pubmed Link

2012; Chaudhry, H., Mundi, R., Einhorn, T.A., Russell, T.A., Parvizi, J. and Bhandari, M. Variability in the approach to total hip arthroplasty in patients with displaced femoral neck fractures. J Arthroplasty: 27; 4. 569 - 574. Pubmed Link

2012; Abrahamsen, B. and Einhorn, T.A. Beyond a reasonable doubt? Bisphosphonates and atypical femur fractures. Bone: 50; 5. 1196 - 1200. Pubmed Link

2011; Nauth, A., McKee, M.D., Einhorn, T.A., Watson, J.T., Li, R. and Schemitsch, E.H. Managing bone defects. J Orthop Trauma: 25; 8. 462 - 466. Pubmed Link

2011; Marsell, R. and Einhorn, T.A. The biology of fracture healing. Injury: 42; 6. 551 - 555. Pubmed Link

2011; Giannoudis, P.V., Jones, E. and Einhorn, T.A. Fracture healing and bone repair. Injury: 42; 6. 549 - 550. Pubmed Link

2011; Einhorn, T.A. New technologies for the enhancement of skeletal repair: Challenges and opportunities. Indian J Orthop: 45; 6. 489 - 491. Pubmed Link

2011; Briel, M., Sprague, S., Heels-Ansdell, D., Guyatt, G., Bhandari, M., Blackhouse, G., Sanders, D., Schemitsch, E., Swiontkowski, M., Tornetta P, 3.r., Walter, S.D. and Goeree, R. Economic evaluation of reamed versus unreamed intramedullary nailing in patients with closed and open tibial fractures: results from the study to prospectively evaluate reamed intramedullary nails in patients with tibial fractures (SPRINT). Value Health: 14; 4. 450 - 457. Pubmed Link

2010; Nauth, A., Giannoudis, P.V., Einhorn, T.A., Hankenson, K.D., Friedlaender, G.E., Li, R. and Schemitsch, E.H. Growth factors: beyond bone morphogenetic proteins. J Orthop Trauma: 24; 9. 543 - 546. Pubmed Link

2010; Cox, G., Einhorn, T.A., Tzioupis, C. and Giannoudis, P.V. Bone-turnover markers in fracture healing. J Bone Joint Surg Br: 92; 3. 329 - 334. Pubmed Link

2010; Abdul-Hadi, O., Parvizi, J., Austin, M.S., Viscusi, E.R. and Einhorn, T.A. Nonsteroidal anti-inflammatory drugs in orthopaedics. Instr Course Lect: 59; 607 - 617. Pubmed Link

2009; Marsell, R. and Einhorn, T.A. The role of endogenous bone morphogenetic proteins in normal skeletal repair. Injury: 40 Suppl 3; S4 - 7. Pubmed Link

2009; Giannoudis, P.V. and Einhorn, T.A. Bone morphogenetic proteins in musculoskeletal medicine. Injury: 40 Suppl 3; S1 - 3. Pubmed Link

2008; Wan, C., Gilbert, S.R., Wang, Y., Cao, X.M., Shen, X., Ramaswamy, G., Jacobsen, K.A., Alaql, Z.S., Gerstenfeld, L.C., Einhorn, T.A., Eberhardt, A.W., Deng, L., Guldberg, R.E. and Clemens, T.L. Role of hypoxia inducible factor-1 alpha pathway in bone regeneration. J Musculoskelet Neuronal Interact: 8; 4. 323 - 324. Pubmed Link

2008; Sung, J.K., Levin, R., Siegel, J., Einhorn, T.A., Creevy, W.R. and Tornetta P, 3.r. Reuse of external fixation components: a randomized trial. J Orthop Trauma: 22; 2. 126 - 30; discussion 130-1. Pubmed Link

2008; Barnes, G.L., Kakar, S., Vora, S., Morgan, E.F., Gerstenfeld, L.C. and Einhorn, T.A. Stimulation of fracture-healing with systemic intermittent parathyroid hormone treatment. J Bone Joint Surg Am: 90 Suppl 1; 120 - 127. Pubmed Link

2008; Bajammal, S.S., Zlowodzki, M., Lelwica, A., Tornetta P, 3.r., Einhorn, T.A., Buckley, R., Leighton, R., Russell, T.A., Larsson, S. and Bhandari, M. The use of calcium phosphate bone cement in fracture treatment. A meta-analysis of randomized trials. J Bone Joint Surg Am: 90; 6. 1186 - 1196. Pubmed Link

2008; Axelrad, T.W., Steen, B., Lowenberg, D.W., Creevy, W.R. and Einhorn, T.A. Heterotopic ossification after the use of commercially available recombinant human bone morphogenetic proteins in four patients. J Bone Joint Surg Br: 90; 12. 1617 - 1622. Pubmed Link

2007; Giannoudis, P.V., Kanakaris, N.K. and Einhorn, T.A. Interaction of bone morphogenetic proteins with cells of the osteoclast lineage: review of the existing evidence. Osteoporos Int: 18; 12. 1565 - 1581. Pubmed Link

2007; Giannoudis, P.V., Einhorn, T.A. and Marsh, D. Fracture healing: the diamond concept. Injury: 38 Suppl 4; S3 - 6. Pubmed Link

2007; De Long, W.G., Jr., Einhorn, T.A., Koval, K., McKee, M., Smith, W., Sanders, R. and Watson, T. Bone grafts and bone graft substitutes in orthopaedic trauma surgery. A critical analysis. J Bone Joint Surg Am: 89; 3. 649 - 658. Pubmed Link

2007; Bishop, G.B. and Einhorn, T.A. Current and future clinical applications of bone morphogenetic proteins in orthopaedic trauma surgery. Int Orthop: 31; 6. 721 - 727. Pubmed Link

2007; Axelrad, T.W., Kakar, S. and Einhorn, T.A. New technologies for the enhancement of skeletal repair. Injury: 38 Suppl 1; S49 - 62. Pubmed Link

2006; Gruber, R., Koch, H., Doll, B.A., Tegtmeier, F., Einhorn, T.A. and Hollinger, J.O. Fracture healing in the elderly patient. Exp Gerontol: 41; 11. 1080 - 1093. Pubmed Link

2006; Gerstenfeld, L.C., Alkhiary, Y.M., Krall, E.A., Nicholls, F.H., Stapleton, S.N., Fitch, J.L., Bauer, M., Kayal, R., Graves, D.T., Jepsen, K.J. and Einhorn, T.A. Three-dimensional reconstruction of fracture callus morphogenesis. J Histochem Cytochem: 54; 11. 1215 - 1228. Pubmed Link

2005; Morris, C.D. and Einhorn, T.A. Bisphosphonates in orthopaedic surgery. J Bone Joint Surg Am: 87; 7. 1609 - 1618. Pubmed Link

2005; Kain, M.S. and Einhorn, T.A. Recombinant human bone morphogenetic proteins in the treatment of fractures. Foot Ankle Clin: 10; 4. 639 - 50, viii. Pubmed Link

2005; Jarvinen, T.L., Sievanen, H., Jokihaara, J. and Einhorn, T.A. Revival of bone strength: the bottom line. J Bone Miner Res: 20; 5. 717 - 720. Pubmed Link

2005; Bhandari, M., Bajammal, S., Guyatt, G.H., Griffith, L., Busse, J.W., Schunemann, H. and Einhorn, T.A. Effect of bisphosphonates on periprosthetic bone mineral density after total joint arthroplasty. A meta-analysis. J Bone Joint Surg Am: 87; 2. 293 - 301. Pubmed Link

2004; Mont, M.A., Ragland, P.S., Biggins, B., Friedlaender, G., Patel, T., Cook, S., Etienne, G., Shimmin, A., Kildey, R., Rueger, D.C. and Einhorn, T.A. Use of bone morphogenetic proteins for musculoskeletal applications. An overview. J Bone Joint Surg Am: 86-A Suppl 2; 41 - 55. Pubmed Link

2003; Einhorn, T.A., Majeska, R.J., Mohaideen, A., Kagel, E.M., Bouxsein, M.L., Turek, T.J. and Wozney, J.M. A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair. J Bone Joint Surg Am: 85-A; 8. 1425 - 1435. Pubmed Link

2003; Einhorn, T.A. The structural properties of normal and osteoporotic bone. Instr Course Lect: 52; 533 - 539. Pubmed Link

2003; Einhorn, T.A. Cox-2: Where are we in 2003? - The role of cyclooxygenase-2 in bone repair. Arthritis Res Ther: 5; 1. 5 - 7. Pubmed Link

2003; Bono, C.M. and Einhorn, T.A. Overview of osteoporosis: pathophysiology and determinants of bone strength. Eur Spine J: 12 Suppl 2; S90 - 6. Pubmed Link

2002; Lieberman, J.R., Daluiski, A. and Einhorn, T.A. The role of growth factors in the repair of bone. Biology and clinical applications. J Bone Joint Surg Am: 84-A; 6. 1032 - 1044. Pubmed Link

2001; Einhorn, T.A. and Lee, C.A. Bone regeneration: new findings and potential clinical applications. J Am Acad Orthop Surg: 9; 3. 157 - 165. Pubmed Link

1999; Holzer, G., Majeska, R.J., Lundy, M.W., Hartke, J.R. and Einhorn, T.A. Parathyroid hormone enhances fracture healing. A preliminary report. Clin Orthop Relat Res: 366. 258 - 263. Pubmed Link

1999; Bostrom, M.P., Saleh, K.J. and Einhorn, T.A. Osteoinductive growth factors in preclinical fracture and long bone defects models. Orthop Clin North Am: 30; 4. 647 - 658. Pubmed Link

1998; Mirsky, E.C. and Einhorn, T.A. Bone densitometry in orthopaedic practice. J Bone Joint Surg Am: 80; 11. 1687 - 1698. Pubmed Link

1998; Lee, F.Y., Choi, Y.W., Behrens, F.F., DeFouw, D.O. and Einhorn, T.A. Programmed removal of chondrocytes during endochondral fracture healing. J Orthop Res: 16; 1. 144 - 150. Pubmed Link

1998; Jazrawi, L.M., Majeska, R.J., Klein, M.L., Kagel, E., Stromberg, L. and Einhorn, T.A. Bone and cartilage formation in an experimental model of distraction osteogenesis. J Orthop Trauma: 12; 2. 111 - 116. Pubmed Link

1998; Einhorn, T.A. The cell and molecular biology of fracture healing. Clin Orthop Relat Res: 355 Suppl. S7 - 21. Pubmed Link

1998; Einhorn, T.A. Breakout session. 1: Definitions of fracture repair. Clin Orthop Relat Res: 355 Suppl. Pubmed Link

1997; Melton LJ, 3.r., Thamer, M., Ray, N.F., Chan, J.K., Chesnut CH, 3.r., Einhorn, T.A., Johnston, C.C., Raisz, L.G., Silverman, S.L. and Siris, E.S. Fractures attributable to osteoporosis: report from the National Osteoporosis Foundation. J Bone Miner Res: 12; 1. 16 - 23. Pubmed Link

1996; Einhorn, T.A. Enhancement of fracture healing. Instr Course Lect: 45; 401 - 416. Pubmed Link

1995; Kagel, E.M., Majeska, R.J. and Einhorn, T.A. Effects of diabetes and steroids on fracture healing. Curr Opin Orthop: 6; 5. 7 - 13. Pubmed Link

1994; Molinari, R.W., Yang, E.C., Strauss, E. and Einhorn, T.A. Timing of internal fixation in low-velocity extremity gunshot fractures. Contemp Orthop: 29; 5. 335 - 339. Pubmed Link

1993; Lucas, T.S. and Einhorn, T.A. Osteoporosis: The Role of the Orthopaedist. J Am Acad Orthop Surg: 1; 1. 48 - 56. Pubmed Link

1988; Einhorn, T.A., Gundberg, C.M., Devlin, V.J. and Warman, J. Fracture healing and osteocalcin metabolism in vitamin K deficiency. Clin Orthop Relat Res: 237. 219 - 225. Pubmed Link

1988; Einhorn, T.A., Boskey, A.L., Gundberg, C.M., Vigorita, V.J., Devlin, V.J. and Beyer, M.M. The mineral and mechanical properties of bone in chronic experimental diabetes. J Orthop Res: 6; 3. 317 - 323. Pubmed Link

1986; Phelps, K.R., Einhorn, T.A., Vigorita, V.J., Lundin, A.P. and Friedman, E.A. Fracture healing with deferoxamine therapy in a patient with aluminum-associated osteomalacia. ASAIO Trans: 32; 1. 198 - 200. Pubmed Link

1986; Einhorn, T.A., Vigorita, V.J. and Teitcher, J.B. Hyperphosphatasemia in an adult. Clinical, roentgenographic, and histomorphometric findings and comparison to classical Paget's disease. Clin Orthop Relat Res: 204. 253 - 260. Pubmed Link

1984; Lane, J.M., Healey, J.H., Schwartz, E., Vigorita, V.J., Schneider, R., Einhorn, T.A., Suda, M. and Robbins, W.C. Treatment of osteoporosis with sodium fluoride and calcium: effects on vertebral fracture incidence and bone histomorphometry. Orthop Clin North Am: 15; 4. 729 - 745. Pubmed Link

1984; Einhorn, T.A., Lane, J.M., Burstein, A.H., Kopman, C.R. and Vigorita, V.J. The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study. J Bone Joint Surg Am: 66; 2. 274 - 279. Pubmed Link